Anti-Thyroid Peroxidase Antibody (TPOAb)

METHODOLOGY

Radioimmunoassay

 

PERFORMED  

 

Tuesday & Thursday

REPORTED  

3 days

COLLECT  

 

One 6 mL RT (Min: 4 mL RT)

TRANSPORT  

 

2.0 mL refrigerated serum (Min: 0.5 mL)


STABILITY  


Stored at 2 - 8°C until used; Stable if frozen at - 20°C 

UNACCEPTABLE SPECIMENS  

Whole blood/Plasma; Slightly and moderately lipemic, hemolyzed or icteric samples are acceptable. Samples that are grossly lipemic, icteric or hemolyzed are to be brought to the attention of the Supervisory Staff for approval.


REFERENCE RANGE

 

 <1.0 IU/mL


CPT CODE

86376


INFORMATION

 

 Thyroid peroxidase autoantibodies (TPOAb) are of pathological importance because they are present in the majority of Hashimoto’s thyroiditis patients and correlate with the active phase of the disease.  Unlike thyroglobulin autoantibodies (TgAb), they may damage thyroid cells by complement fixation.  The detection of thyroid peroxidase autoantibodies (TPOAb) and thyroglobulin autoantibodies (TgAb), and the measurement of thyroid stimulating hormone, have been used in determining the diagnosis and management of autoimmune thyroid disorders.

USC ENDOCRINE SERVICES LABORATORY
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Email: endolab@usc.edu

The USC Endocrine Services Laboratory is licensed by the State of California, Department of Health Services, and accredited by the College of American Pathologists, and certified by Medicare according to the provisions of the U.S. Department of Health and Human Services Clinical Laboratory Improvement Act of 1988.

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