Anti-Thyroglobulin Antibody (TgAb)

 

METHODOLOGY


Radioimmunoassay

PERFORMED  

 

Monday - Friday

 

REPORTED

 

Next Working Day


COLLECT  

 

One 6mL RT (Min: 4 mL RT)

TRANSPORT  

 

1.0 mL refrigerated serum (Min: 0.5 mL)


STABILITY  


Stored at 2 - 8°C until used; Stable if frozen at - 20°C  

UNACCEPTABLE SPECIMENS  

 

Whole blood/Plasma; Slightly and moderately lipemic, hemolyzed or icteric samples are acceptable.  Samples that are grossly lipemic, icteric or hemolyzed are to be brought to the attention of the Supervisory Staff for approval.


REFERENCE RANGE

 

 <0.4 U/mL


CPT CODE

86800


INFORMATION

 

   This highly sensitive, direct radioimmunoassay system is based on the use of a highly purified, stable preparation of 125I labeled Thyroglobulin.  The assay is standardized against the MRC Thyroglobulin Auto-antibody First International Reference Preparation (Coded 65/93).

Measurement of thyroglobulin auto-antibodies can be of considerable value in the diagnosis of thyroid diseases, such as autoimmune thyroiditis, Graves' disease, endemic goiter and subacute thyroiditis.  These measurements when used as part of a thyroid autoimmune diagnostic profile, which would include Anti Thyroid Peroxidase Antibody and Thyrotropin Receptor antibody, can be very useful in the differential diagnosis and management of thyroid disease.  TgAb is always to be run in conjunction with Thyroglobulin (Tg) sera in order to conform to NACB guidelines (Thyroid 13:1, 2003).

USC ENDOCRINE SERVICES LABORATORY
126 W. Del Mar Blvd 
Pasadena, CA 91105-2508
Phone: (855) 224-7111
Fax: (855) 224-7123

Email: endolab@usc.edu

The USC Endocrine Services Laboratory is licensed by the State of California, Department of Health Services, and accredited by the College of American Pathologists, and certified by Medicare according to the provisions of the U.S. Department of Health and Human Services Clinical Laboratory Improvement Act of 1988.

1975 - 2020. All Rights Reserved.